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Methionine, in turn, is required for the synthesis of S-adenosylmethionine (SAMe), a methyl group donor used in many biological methylation reactions, including the methylation of a number of sites within DNA and RNA

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Also, could glutamate conversion to α-ketoglutarate be catalyzed by aspartate aminotransferase in one potential subfraction and by GDH in the other

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