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However, while early studies and preclinical findings are promising, robust clinical data directly supporting the efficacy of this specific combination as a standardized therapeutic strategy remains limited

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Although adverse reactions to intravenous, intramuscular or subcutaneous injection of 0.9% benzyl alcohol are not known to occur in man, experimental studies of small volume parenteral preparations containing 0.9% benzyl alcohol in several species of animals have indicated that an estimated intravenous dose up to 30 mL may be safely given to an adult without toxic effects